Naturally Occurring Carcinogens, Mutagens and Modulators of Carcinogenesis

Naturally Occurring Orally Active Dietary Carcinogens

Rapid detection of mutagens and carcinogens.

SUMMARY Bacteria deficient in DNA polymerase are much more sensitive to agents that alter cellular DNA than the parent strain from which they were derived. Advantage can be taken of this greater sensitivity to screen for potential mutagens and carcinogens.

Structural Alerts of Mutagens and Carcinogens

This paper summarizes the evidence on the Structural Alerts of mutagenicity and carcinogenicity. The Structural Alerts are molecular substructures or reactive groups that are related to the carcinogenic and mutagenic properties of the chemicals, and represent a sort of “codification” of a long series of studies aimed at highlighting the mechanisms of action of the mutagenic and carcinogenic che...

Mutagens and Carcinogens in the Diet

however, it is well written, with excellent transitions from one chapter to the next, and the historical approach used by the authors makes the book timeless. I recommend that everyone interested in understanding the mechanisms of G-protein signal transduction read this volume. Pariza notes in the preface that legislative and regulatory initiatives aimed at controlling or eliminating carcinogen...

Carcinogens are mutagens: their detection and classification.

We detect mutagens by using a special set of bacterial tester strains. We have described our test system for mutagen and carcinogen detection in a series of recent papers. I will give here only a summary of some of these results, omitting references to other work, which is credited in our original papers. A simple procedure for combining human (or rat) liver for carcinogen activation and the ba...